Lens-induced myopization and body weight in young guinea pigs.
BMC Ophthalmol
; 24(1): 6, 2024 Jan 03.
Article
en En
| MEDLINE
| ID: mdl-38172796
ABSTRACT
BACKGROUND:
To investigate the relationship between body weight and Axial length in guinea pigs.METHODS:
Forty pigmented guinea pigs were randomly divided into two groups, namely control group and negative lens-induced myopization (LIM) group. After measuring the baseline axial length and body weight (BW), guinea pigs of LIM group received bilateral negative lens-induced myopization using - 10.0 diopters lenses. One week later, the lenses were removed and biometric and ophthalmoscopic examinations were repeated.RESULTS:
Two groups of guinea pigs showed no statistical difference in initial body weight and eye axis length. Compared to the control group, the lens-induced group had a lower weight (P = 0.02) and a longer axial length (P < 0.01) at the end of study Neither at baseline nor at week 1 did AL correlate with BW in both groups (Control Baseline r = 0.306, P = 0.19; Control Week1 r = 0.333, P = 0.15; LIM Baseline r=-0.142, P = 0.55; LIM Week 1 r = 0.189, P = 0.42). Lens-induction had a significant effect on axial elongation (P < 0.01) while body weight had no impact on such aspect (P > 0.05).CONCLUSION:
In guinea pigs of the same age, axial length was not correlated with body weight. Also, baseline body weight had no impact on natural axial length growth or lens-induced myopia. Lens-induction caused a significant reduction in body weight gain.Palabras clave
Texto completo:
1
Banco de datos:
MEDLINE
Asunto principal:
Cristalino
/
Miopía
Tipo de estudio:
Etiology_studies
Límite:
Animals
Idioma:
En
Año:
2024
Tipo del documento:
Article