Correlation of toxoplasmosis with smallforgestationalage newborns.
Bratisl Lek Listy
; 125(2): 92-95, 2024.
Article
en En
| MEDLINE
| ID: mdl-38219061
ABSTRACT
BACKGROUND:
Toxoplasma gondii infection in pregnant women could lead to significant changes during the pregnancy, affect the outcomes of pregnancy and the timing of labour. Smallforgestationalage (SGA) newborns are defined by birthweight below the 10th percentile for gestational age. We tested an association between latent toxoplasmosis in pregnant women and deliveries of SGA babies. MATERIAL ANDMETHODS:
For testing, we included 1,647 women who gave birth to a singleton baby at ≥ 37 weeks of gestation. The complement-fixation test (CFT) and enzyme-linked immunosorbent assay (ELISA) tests for IgG and IgM were used. The latent form of toxoplasmosis was defined as a CFT titre of 18 or higher, together with index positivity IgG ELISA > 1.1 and negative IgM.RESULTS:
There were 406 (24.7 %) women positive, and 1,241 (75.3 %) women negative for latent toxoplasmosis. Of all deliveries. 190 were SGApositive and 1,457 were SGAnegative. Our study found a statistically significant association between latent toxoplasmosis and SGA foetuses born at term. The Pearson chi-square model was statistically significant (χ2(1) = 7.365, p = .007). The odds ratio was 1.567.CONCLUSION:
Pregnant women with latent toxoplasmosis giving birth at ≥ 37 weeks of gestation have a 1.567 times higher risk of delivering an SGA baby (Tab. 2, Fig. 1, Ref. 30).Palabras clave
Texto completo:
1
Banco de datos:
MEDLINE
Asunto principal:
Toxoplasma
/
Toxoplasmosis
Límite:
Female
/
Humans
/
Male
/
Newborn
/
Pregnancy
Idioma:
En
Año:
2024
Tipo del documento:
Article