Fisher's Geometric Model as a Tool to Study Speciation.
Cold Spring Harb Perspect Biol
; 16(7)2024 Jul 01.
Article
en En
| MEDLINE
| ID: mdl-38253415
ABSTRACT
Interactions between alleles and across environments play an important role in the fitness of hybrids and are at the heart of the speciation process. Fitness landscapes capture these interactions and can be used to model hybrid fitness, helping us to interpret empirical observations and clarify verbal models. Here, we review recent progress in understanding hybridization outcomes through Fisher's geometric model, an intuitive and analytically tractable fitness landscape that captures many fitness patterns observed across taxa. We use case studies to show how the model parameters can be estimated from different types of data and discuss how these estimates can be used to make inferences about the divergence history and genetic architecture. We also highlight some areas where the model's predictions differ from alternative incompatibility-based models, such as the snowball effect and outlier patterns in genome scans.
Texto completo:
1
Banco de datos:
MEDLINE
Asunto principal:
Especiación Genética
Tipo de estudio:
Prognostic_studies
Límite:
Animals
Idioma:
En
Año:
2024
Tipo del documento:
Article