Utilising biosensor-based approaches for identifying neurotropic viruses.
Rev Med Virol
; 34(1): e2513, 2024 Jan.
Article
en En
| MEDLINE
| ID: mdl-38282404
ABSTRACT
Neurotropic viruses, with their ability to invade the central nervous system, present a significant public health challenge, causing a spectrum of neurological diseases. Clinical manifestations of neurotropic viral infections vary widely, from mild to life-threatening conditions, such as HSV-induced encephalitis or poliovirus-induced poliomyelitis. Traditional diagnostic methods, including polymerase chain reaction, serological assays, and imaging techniques, though valuable, have limitations. To address these challenges, biosensor-based methods have emerged as a promising approach. These methods offer advantages such as rapid results, high sensitivity, specificity, and potential for point-of-care applications. By targeting specific biomarkers or genetic material, biosensors utilise technologies like surface plasmon resonance and microarrays, providing a direct and efficient means of diagnosing neurotropic infections. This review explores the evolving landscape of biosensor-based methods, highlighting their potential to enhance the diagnostic toolkit for neurotropic viruses.
Palabras clave
Texto completo:
1
Banco de datos:
MEDLINE
Asunto principal:
Poliomielitis
/
Virus
/
Técnicas Biosensibles
/
Enfermedades del Sistema Nervioso
Límite:
Humans
Idioma:
En
Año:
2024
Tipo del documento:
Article