Orbital Development in Children with Retinoblastoma: An Imaging-Based Study.
Semin Ophthalmol
; 39(5): 369-375, 2024 Jul.
Article
en En
| MEDLINE
| ID: mdl-38329101
ABSTRACT
PURPOSE:
To examine whether children treated for Retinoblastoma (Rb) have impaired orbital development.METHODS:
A retrospective case series was performed among children with Rb treated at a single medical center from 2004 to 2020. Orbital volumes and measurements were assessed by 3-dimensional image processing software. The main outcome measures were differences in orbital growth between Rb and non-Rb eyes assessed at last follow-up.RESULTS:
Among 44 patients included (mean age 16.09 ± 18.01 months), a positive correlation between age and orbital volume was observed only in the uninvolved, healthy eyes (p = .03). In unilateral cases, orbital growth in the horizontal, vertical, and depth planes was smaller on the affected side compared to the healthy eyes (p < .05). Orbits that underwent enucleation showed decreased growth over time compared to those treated conservatively (p = .017).CONCLUSIONS:
Orbital growth rate is slower in the orbits of children treated for Rb compared to healthy orbits. Enucleation negatively affects orbital growth.Palabras clave
Texto completo:
1
Banco de datos:
MEDLINE
Asunto principal:
Órbita
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Retinoblastoma
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Neoplasias de la Retina
Límite:
Child, preschool
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Female
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Humans
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Infant
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Male
Idioma:
En
Año:
2024
Tipo del documento:
Article