Impact of haemoglobin A1c on wound infection in patients with diabetes with implanted synthetic graft.
J Wound Care
; 33(2): 136-142, 2024 Feb 02.
Article
en En
| MEDLINE
| ID: mdl-38329828
ABSTRACT
OBJECTIVE:
The aim of this study was to assess the relationship between haemoglobin A1c (HbA1c) values and operative wound infection.METHOD:
During the period from 2013-2016, consecutive patients with type 2 diabetes were prospectively evaluated. Data were retrospectively analysed. All included patients were admitted for an elective surgical procedure, requiring the use of prosthetic graft in a groin wound. The patients were divided into two groups according to their preoperative HbA1c values. The main outcome was groin wound infection. The association between preoperative long-term glycoregulation and wound infection was evaluated, as well as the impact of postoperative glycaemic values, regardless of the level of HbA1c.RESULTS:
Of the 93 participating patients, wound infection occurred in 20 (21.5%). Wound infection occurred in 28.2% of patients with uncontrolled diabetes (HbA1c >7%) and 16.7% of patients with controlled diabetes (HbA1c <7%); however, the difference did not reach statistical significance (p=0.181). In regression modelling, operative time (p=0.042) was a significant predictor of wound infection, while patients' age (p=0.056) was on the borderline of statistical significance. Females had a higher probability for wound infection (odds ratio (OR) 1.739; 95% confidence interval (CI)0.483-6.265), but there was no statistical significance (p=0.397). Patients with elevated levels of HbA1c had a higher chance of wound infection compared with patients with controlled diabetes (OR 2.243; 95% CI 0.749-6.716), nevertheless, this was not statistically significant (p=0.149).CONCLUSION:
We found no statistically significant correlation between elevated values of preoperative HbA1c and postoperative groin wound infection.Palabras clave
Texto completo:
1
Banco de datos:
MEDLINE
Asunto principal:
Diabetes Mellitus Tipo 2
Tipo de estudio:
Observational_studies
/
Prognostic_studies
/
Risk_factors_studies
Límite:
Female
/
Humans
Idioma:
En
Año:
2024
Tipo del documento:
Article