IR76b-expressing neurons in Drosophila melanogaster are necessary for associative reward learning of an amino acid mixture.
Biol Lett
; 20(2): 20230519, 2024 02.
Article
en En
| MEDLINE
| ID: mdl-38351746
ABSTRACT
Learning where to find nutrients while at the same time avoiding toxic food is essential for survival of any animal. Using Drosophila melanogaster larvae as a study case, we investigate the role of gustatory sensory neurons expressing IR76b for associative learning of amino acids, the building blocks of proteins. We found surprising complexity in the neuronal underpinnings of sensing amino acids, and a functional division of sensory neurons. We found that the IR76b receptor is dispensable for amino acid learning, whereas the neurons expressing IR76b are specifically required for the rewarding but not the punishing effect of amino acids. This unexpected dissociation in neuronal processing of amino acids for different behavioural functions provides a study case for functional divisions of labour in gustatory systems.
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Texto completo:
1
Banco de datos:
MEDLINE
Asunto principal:
Proteínas de Drosophila
/
Drosophila melanogaster
Tipo de estudio:
Risk_factors_studies
Límite:
Animals
Idioma:
En
Año:
2024
Tipo del documento:
Article