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Neutrophils are itching to specialize.
Hiroki, Carlos H; Yipp, Bryan G.
  • Hiroki CH; Department of Critical Care, Cumming School of Medicine, University of Calgary, Calgary, AB, Canada; Calvin, Phoebe and Joan Snyder Institute for Chronic Diseases, Cumming School of Medicine, University of Calgary, Calgary, AB, Canada.
  • Yipp BG; Department of Critical Care, Cumming School of Medicine, University of Calgary, Calgary, AB, Canada; Calvin, Phoebe and Joan Snyder Institute for Chronic Diseases, Cumming School of Medicine, University of Calgary, Calgary, AB, Canada. Electronic address: bgyipp@ucalgary.ca.
Immunity ; 57(2): 198-200, 2024 Feb 13.
Article en En | MEDLINE | ID: mdl-38354698
ABSTRACT
Neutrophils are heterogeneous, but the mechanisms underlying their ability to polarize remain unclear. In this issue of Immunity, Gour et al. demonstrate that the GPCR Mrgpra1 and the neuropeptide NPFF, molecules involved in pain and itch, direct neutrophil polarization that impacts host defense and pneumonia susceptibility.
Asunto(s)

Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Neuropéptidos / Neutrófilos Límite: Humans Idioma: En Año: 2024 Tipo del documento: Article

Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Neuropéptidos / Neutrófilos Límite: Humans Idioma: En Año: 2024 Tipo del documento: Article