Age at lung cancer diagnosis in females versus males who never smoke by race and ethnicity.
Br J Cancer
; 130(8): 1286-1294, 2024 May.
Article
en En
| MEDLINE
| ID: mdl-38388856
ABSTRACT
BACKGROUND:
We characterized age at diagnosis and estimated sex differences for lung cancer and its histological subtypes among individuals who never smoke.METHODS:
We analyzed the distribution of age at lung cancer diagnosis in 33,793 individuals across 8 cohort studies and two national registries from East Asia, the United States (US) and the United Kingdom (UK). Student's t-tests were used to assess the study population differences (Δ years) in age at diagnosis comparing females and males who never smoke across subgroups defined by race/ethnicity, geographic location, and histological subtypes.RESULTS:
We found that among Chinese individuals diagnosed with lung cancer who never smoke, females were diagnosed with lung cancer younger than males in the Taiwan Cancer Registry (n = 29,832) (Δ years = -2.2 (95% confidence interval (CI)-2.5, -1.9), in Shanghai (n = 1049) (Δ years = -1.6 (95% CI-2.9, -0.3), and in Sutter Health and Kaiser Permanente Hawai'i in the US (n = 82) (Δ years = -11.3 (95% CI -17.7, -4.9). While there was a suggestion of similar patterns in African American and non-Hispanic White individuals. the estimated differences were not consistent across studies and were not statistically significant.CONCLUSIONS:
We found evidence of sex differences for age at lung cancer diagnosis among individuals who never smoke.
Texto completo:
1
Banco de datos:
MEDLINE
Asunto principal:
Etnicidad
/
Neoplasias Pulmonares
Límite:
Female
/
Humans
/
Male
País como asunto:
America do norte
/
Asia
Idioma:
En
Año:
2024
Tipo del documento:
Article