Chemically Cross-Linked Hammerhead Ribozyme as an Efficient RNA Interference Tool.

Wang, Liang-Liang; Wu, Chao-Qun; Zhang, Qiu-Long; Wang, Yang; Liu, Yan; Yang, Wen-Jian; Ye, Sen-Lin; Tian, Yongqiang; Xu, Liang.

Wang LL; MOE Key Laboratory of Bioinorganic and Synthetic Chemistry, School of Chemistry, Sun Yat-Sen University, Guangzhou 510275, China.
Wu CQ; School of Biological and Pharmaceutical Engineering, Lanzhou Jiaotong University, Lanzhou 730070, China.
Zhang QL; MOE Key Laboratory of Bioinorganic and Synthetic Chemistry, School of Chemistry, Sun Yat-Sen University, Guangzhou 510275, China.
Wang Y; MOE Key Laboratory of Bioinorganic and Synthetic Chemistry, School of Chemistry, Sun Yat-Sen University, Guangzhou 510275, China.
Liu Y; School of Pharmacy and Medical Technology, Key Laboratory of Pharmaceutical Analysis and Laboratory Medicine of Fujian Province, Putian University, Putian 351100, China.
Yang WJ; MOE Key Laboratory of Bioinorganic and Synthetic Chemistry, School of Chemistry, Sun Yat-Sen University, Guangzhou 510275, China.
Ye SL; MOE Key Laboratory of Bioinorganic and Synthetic Chemistry, School of Chemistry, Sun Yat-Sen University, Guangzhou 510275, China.
Tian Y; MOE Key Laboratory of Bioinorganic and Synthetic Chemistry, School of Chemistry, Sun Yat-Sen University, Guangzhou 510275, China.
Xu L; MOE Key Laboratory of Bioinorganic and Synthetic Chemistry, School of Chemistry, Sun Yat-Sen University, Guangzhou 510275, China.

J Am Chem Soc ; 146(10): 6665-6674, 2024 03 13.

Article en En | MEDLINE | ID: mdl-38412223

Asunto(s)

ARN Catalítico; ARN Catalítico/química; Interferencia de ARN; ARN Interferente Pequeño/metabolismo; Procesamiento Proteico-Postraduccional; Conformación de Ácido Nucleico