Differential functional organization of amygdala-medial prefrontal cortex networks in macaque and human.
Commun Biol
; 7(1): 269, 2024 Mar 05.
Article
en En
| MEDLINE
| ID: mdl-38443489
ABSTRACT
Over the course of evolution, the amygdala (AMG) and medial frontal cortex (mPFC) network, involved in behavioral adaptation, underwent structural changes in the old-world monkey and human lineages. Yet, whether and how the functional organization of this network differs remains poorly understood. Using resting-state functional magnetic resonance imagery, we show that the functional connectivity (FC) between AMG nuclei and mPFC regions differs between humans and awake macaques. In humans, the AMG-mPFC FC displays U-shaped pattern along the corpus callosum a positive FC with the ventromedial prefrontal (vmPFC) and anterior cingulate cortex (ACC), a negative FC with the anterior mid-cingulate cortex (MCC), and a positive FC with the posterior MCC. Conversely, in macaques, the negative FC shifted more ventrally at the junction between the vmPFC and the ACC. The functional organization divergence of AMG-mPFC network between humans and macaques might help understanding behavioral adaptation abilities differences in their respective socio-ecological niches.
Texto completo:
1
Banco de datos:
MEDLINE
Asunto principal:
Corteza Prefrontal
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Macaca
Límite:
Animals
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Humans
Idioma:
En
Año:
2024
Tipo del documento:
Article