There and back again? A B cell's tale on responses and spatial distribution in teleosts.
Fish Shellfish Immunol
; 148: 109479, 2024 May.
Article
en En
| MEDLINE
| ID: mdl-38467322
ABSTRACT
Teleost B cells are of special interest due to their evolutionary position and involvement in vaccine-induced adaptive immune responses. While recent progress has revealed uneven distribution of B cell subsets across the various immune sites and that B cells are one of the early responders to infection, substantial knowledge gaps persist regarding their immunophenotypic profile, functional mechanisms, and what factors lead them to occupy different immune niches. This review aims to assess the current understanding of B cell diversity, their spatial distribution in various systemic and peripheral immune sites, how B cell responses initiate, the sites where these responses develop, their trafficking, and the locations where long-term B cell responses take place.
Palabras clave
Texto completo:
1
Banco de datos:
MEDLINE
Asunto principal:
Vacunas
/
Linfocitos B
Límite:
Animals
Idioma:
En
Año:
2024
Tipo del documento:
Article