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There and back again? A B cell's tale on responses and spatial distribution in teleosts.
Jenberie, Shiferaw; van der Wal, Yorick A; Jensen, Ingvill; Jørgensen, Jorunn B.
  • Jenberie S; Norwegian College of Fishery Science, Faculty of Biosciences, Fisheries and Economics, UiT - the Arctic University of Norway, Tromsø, Norway. Electronic address: shiferaw.jenberie@uit.no.
  • van der Wal YA; MSD Animal Health, Wim de Körverstraat 35, 5831 AN, Boxmeer, the Netherlands.
  • Jensen I; Norwegian College of Fishery Science, Faculty of Biosciences, Fisheries and Economics, UiT - the Arctic University of Norway, Tromsø, Norway.
  • Jørgensen JB; Norwegian College of Fishery Science, Faculty of Biosciences, Fisheries and Economics, UiT - the Arctic University of Norway, Tromsø, Norway.
Fish Shellfish Immunol ; 148: 109479, 2024 May.
Article en En | MEDLINE | ID: mdl-38467322
ABSTRACT
Teleost B cells are of special interest due to their evolutionary position and involvement in vaccine-induced adaptive immune responses. While recent progress has revealed uneven distribution of B cell subsets across the various immune sites and that B cells are one of the early responders to infection, substantial knowledge gaps persist regarding their immunophenotypic profile, functional mechanisms, and what factors lead them to occupy different immune niches. This review aims to assess the current understanding of B cell diversity, their spatial distribution in various systemic and peripheral immune sites, how B cell responses initiate, the sites where these responses develop, their trafficking, and the locations where long-term B cell responses take place.
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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Vacunas / Linfocitos B Límite: Animals Idioma: En Año: 2024 Tipo del documento: Article

Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Vacunas / Linfocitos B Límite: Animals Idioma: En Año: 2024 Tipo del documento: Article