Neurophysiological investigations in a case of primary paroxysmal hemicrania-tic syndrome.
Neurol Sci
; 45(8): 3917-3921, 2024 Aug.
Article
en En
| MEDLINE
| ID: mdl-38523207
ABSTRACT
BACKGROUND:
The association between paroxysmal hemicrania (PH) and trigeminal neuralgia-the so-called PH-tic syndrome-has rarely been described. However, a correct diagnosis is crucial since both disorders require specific treatments. Little is known about pathophysiological mechanisms, and, to date, there are no electrophysiological studies in patients with PH-tic syndrome. CASE We describe the case of a 52-year-old man with a PH-tic syndrome successfully treated with an association of carbamazepine (1200 mg/day) and indomethacin (150 mg/die). Patient underwent trigeminal reflex testing, including blink and masseter inhibitory reflex, and laser-evoked potential (LEP) recording after supraorbital region stimulation in the affected and unaffected side. Both neurophysiological investigations resulted normal; LEPs failed to detect any latency asymmetry between both sides.CONCLUSIONS:
Neurophysiological findings demonstrate for the first time the integrity of somatosensory system in a primary PH-tic syndrome case. Central pathophysiological mechanisms and hypothalamic dysregulation may contribute to the development of this rare syndrome.Palabras clave
Texto completo:
1
Banco de datos:
MEDLINE
Asunto principal:
Neuralgia del Trigémino
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Hemicránea Paroxística
Límite:
Humans
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Male
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Middle aged
Idioma:
En
Año:
2024
Tipo del documento:
Article