The regulation of the PD-1/PD-L1 pathway in imiquimod-induced chronic psoriasis itch and itch sensitization in mouse.

Xu, Zhehao; Wang, Yue; Jiang, Changcheng; Wang, Zhengwei; Cheng, YongFeng; Fan, Manli

Xu, Zhehao; Wang, Yue; Jiang, Changcheng; Wang, Zhengwei; Cheng, YongFeng; Fan, Manli.

Xu Z; Department of Pharmacology, Clinic Medical College, Anhui Medical University, Hefei, China.
Wang Y; Department of Pharmacology, Clinic Medical College, Anhui Medical University, Hefei, China.
Jiang C; Department of Science and Education, Hefei BOE Hospital, Hefei, China.
Wang Z; Department of Pharmacology, Clinic Medical College, Anhui Medical University, Hefei, China.
Cheng Y; Department of Pharmacology, Clinic Medical College, Anhui Medical University, Hefei, China.
Fan M; Department of Pharmacology, Clinic Medical College, Anhui Medical University, Hefei, China.

Mol Pain ; 20: 17448069241252384, 2024.

Article en En | MEDLINE | ID: mdl-38631843

Asunto(s)

Antígeno B7-H1; Imiquimod; Receptor de Muerte Celular Programada 1; Prurito; Psoriasis; Animales; Imiquimod/farmacología; Imiquimod/efectos adversos; Prurito/inducido químicamente; Prurito/metabolismo; Psoriasis/inducido químicamente; Psoriasis/complicaciones; Psoriasis/metabolismo; Receptor de Muerte Celular Programada 1/metabolismo; Antígeno B7-H1/metabolismo; Masculino; Ratones; Transducción de Señal/efectos de los fármacos; Piel/metabolismo; Piel/patología; Ratones Endogámicos C57BL; Enfermedad Crónica

Palabras clave

Imiquimod; PD-1/PD-L1 inhibitor; itch; itch sensitization

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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Prurito / Psoriasis / Antígeno B7-H1 / Receptor de Muerte Celular Programada 1 / Imiquimod Límite: Animals Idioma: En Año: 2024 Tipo del documento: Article

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