[Analysis of factors leading to brain MRI lesions in Wernicke's encephalopathy].
Rinsho Shinkeigaku
; 64(5): 361-363, 2024 May 24.
Article
en Ja
| MEDLINE
| ID: mdl-38644211
ABSTRACT
[Objective] To investigate association between Wernicke encephalopathy (WE) and brain MRI. [Subjects] 26 patients (7 females, mean age 63.9 ± 12.7 years) with WE admitted to our department between May 2008 and September 2022. [Methods] Wernicke's encephalopathy in patients with MRI lesions was defined as "MRI-positive group" (MPG), and those without MRI lesions as "MRI-negative group" (MNG). The following parameters were assessed between the two groups age, sex, alcoholism, neurological symptoms, vitamin B1, lymphocyte, total cholesterol, albumin, and outcome at discharge. [Results] There were 17 patients in MPG. Compared to MNG, MPG had lower rates of alcohol abuse (10.0% vs 77.8%, P = 0.025), lower vitamin B1 (median 10.0â
|ng/ml vs 29.0â
|ng/ml, P < 0.001), and more vitamin B1 treatment dose (median 1900â
|mg vs 600â
|mg, P = 0.016). [Conclusion] Alcoholic WE may be overlooked if the focus is solely on brain MRI findings.
Palabras clave
Texto completo:
1
Banco de datos:
MEDLINE
Asunto principal:
Tiamina
/
Encefalopatía de Wernicke
/
Encéfalo
/
Imagen por Resonancia Magnética
/
Alcoholismo
Límite:
Aged
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Female
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Humans
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Male
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Middle aged
Idioma:
Ja
Año:
2024
Tipo del documento:
Article