Obesity, psychological well-being related measures, and risk of seven non-communicable diseases: evidence from longitudinal studies of UK and US older adults.
Int J Obes (Lond)
; 48(9): 1283-1291, 2024 Sep.
Article
en En
| MEDLINE
| ID: mdl-38824226
ABSTRACT
BACKGROUND:
We examined the role of psychological well-being related measures in explaining the associations between obesity and increased risk of non-communicable diseases (NCDs hypertension, heart disease, stroke, diabetes, arthritis, cancer, and memory-related disease) in older adults.METHODS:
Data were from the English Longitudinal Study of Ageing (ELSA), UK (baseline Wave 4-2008/2009; n = 8127) and the Health and Retirement Study (HRS), US (baseline Waves 9 and 10-2008/2010; n = 12,477). Objective body mass index was used to define obesity. A range of psychological well-being related measures (e.g., depressive symptoms, life satisfaction) was available in ELSA (n = 7) and HRS (n = 15), and an index of overall psychological well-being was developed separately in each study. NCDs were from a self-reported doctor diagnosis and/or other assessments (e.g., biomarker data) in both studies; and in ELSA, NCDs from linked hospital admissions data were examined. Longitudinal associations between obesity status, psychological well-being measures, and NCDs were examined using Cox proportional hazard models (individual NCDs) and Poisson regression (a cumulative number of NCDs). Mediation by psychological well-being related measures was assessed using causal mediation analysis.RESULTS:
Obesity was consistently associated with an increased prospective risk of hypertension, heart disease, diabetes, arthritis, and a cumulative number of NCDs in both ELSA and HRS. Worse overall psychological well-being (index measure) and some individual psychological well-being related measures were associated with an increased prospective risk of heart disease, stroke, arthritis, memory-related disease, and a cumulative number of NCDs across studies. Findings from mediation analyses showed that neither the index of overall psychological well-being nor any individual psychological well-being related measures explained (mediated) why obesity increased the risk of developing NCDs in both studies.CONCLUSION:
Obesity and psychological well-being may independently and additively increase the risk of developing NCDs.
Texto completo:
1
Banco de datos:
MEDLINE
Asunto principal:
Enfermedades no Transmisibles
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Obesidad
Límite:
Aged
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Female
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Humans
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Male
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Middle aged
País como asunto:
America do norte
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Europa
Idioma:
En
Año:
2024
Tipo del documento:
Article