Phytochemical Profiling and Biological Activity of the Methanolic Extracts of Cirsium Monspessulanum (L.) Hill.
Chem Biodivers
; 21(8): e202400944, 2024 Aug.
Article
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| MEDLINE
| ID: mdl-38828873
ABSTRACT
The study of new plant species and the identification of their chemical composition may contribute to the discovery of a new breakthrough substances for pharmacotherapeutical applications. For the first time, we examined antioxidant and antimicrobial activity of 70 %â
v/v methanolic extracts from inflorescences and roots of Cirsium monspessulanum (L.) Hill. obtained by the ASE method. In the (2,2-diphenyl-1-picrylhydrazyl) DPPH analysis, tested extract of inflorescences showed antioxidant activity with an EC50=0.223±0.0479â
mg/mL, and (Cupric Ion Reducting Antioxidant Capacity) CUPRAC test assessed the antiradical activity on 14.95±0.13â
mgTE/g and for roots the values were EC50=0.307±0.0554â
mg/mL and 11.18±0.49â
mgTE/g, respectively. Furthermore, extract from the inflorescences possessed the highest antimicrobial activity against Staphylococcus aureus, Staphylococcus epidermidis and Micrococcus luteus with MIC=1.25â
mg/mL for each. HPLC/ESI-QTOF-MS/MS method identified 7 phenolic acids and 14 flavonoids in inflorescences extract and only 7 phenolic acids in roots extract. To the best of our knowledge, this is the first qualitative analysis of Cirsium monspessulanum (L.) Hill. and all substances were described for the first time.
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Banco de datos:
MEDLINE
Asunto principal:
Staphylococcus aureus
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Extractos Vegetales
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Pruebas de Sensibilidad Microbiana
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Cirsium
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Metanol
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Fitoquímicos
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Antibacterianos
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Antioxidantes
Idioma:
En
Año:
2024
Tipo del documento:
Article