Your browser doesn't support javascript.
loading
Odd-Paired is Involved in Morphological Divergence of Snail-Feeding Beetles.
Konuma, Junji; Fujisawa, Tomochika; Nishiyama, Tomoaki; Kasahara, Masahiro; Shibata, Tomoko F; Nozawa, Masafumi; Shigenobu, Shuji; Toyoda, Atsushi; Hasebe, Mitsuyasu; Sota, Teiji.
  • Konuma J; Department of Biology, Faculty of Science, Toho University, Funabashi, Chiba, Japan.
  • Fujisawa T; Center for Data Science Education and Research, Shiga University, Hikone, Shiga, Japan.
  • Nishiyama T; Research Center for Experimental Modeling of Human Disease, Kanazawa University, Ishikawa, Japan.
  • Kasahara M; Graduate School of Frontier Science, The University of Tokyo, Kashiwa, Chiba, Japan.
  • Shibata TF; National Institute for Basic Biology, Okazaki, Aichi, Japan.
  • Nozawa M; Department of Biological Sciences, Tokyo Metropolitan University, Hachioji, Tokyo, Japan.
  • Shigenobu S; Research Center for Genomics and Bioinformatics, Tokyo Metropolitan University, Hachioji, Tokyo, Japan.
  • Toyoda A; National Institute for Basic Biology, Okazaki, Aichi, Japan.
  • Hasebe M; Department of Genomics and Evolutionary Biology, National Institute of Genetics, Mishima, Shizuoka, Japan.
  • Sota T; National Institute for Basic Biology, Okazaki, Aichi, Japan.
Mol Biol Evol ; 41(6)2024 Jun 01.
Article en En | MEDLINE | ID: mdl-38857185
ABSTRACT
Body shape and size diversity and their evolutionary rates correlate with species richness at the macroevolutionary scale. However, the molecular genetic mechanisms underlying the morphological diversification across related species are poorly understood. In beetles, which account for one-fourth of the known species, adaptation to different trophic niches through morphological diversification appears to have contributed to species radiation. Here, we explored the key genes for the morphological divergence of the slender to stout body shape related to divergent feeding methods on large to small snails within the genus Carabus. We show that the zinc-finger transcription factor encoded by odd-paired (opa) controls morphological variation in the snail-feeding ground beetle Carabus blaptoides. Specifically, opa was identified as the gene underlying the slender to stout morphological difference between subspecies through genetic mapping and functional analysis via gene knockdown. Further analyses revealed that changes in opa cis-regulatory sequences likely contributed to the differences in body shape and size between C. blaptoides subspecies. Among opa cis-regulatory sequences, single nucleotide polymorphisms on the transcription factor binding sites may be associated with the morphological differences between C. blaptoides subspecies. opa was highly conserved in a wide range of taxa, especially in beetles. Therefore, opa may play an important role in adaptive morphological divergence in beetles.
Asunto(s)
Palabras clave

Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Caracoles / Factores de Transcripción / Escarabajos Límite: Animals Idioma: En Año: 2024 Tipo del documento: Article

Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Caracoles / Factores de Transcripción / Escarabajos Límite: Animals Idioma: En Año: 2024 Tipo del documento: Article