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The point on the treatment of arrhythmic storm.
Lazzari, Ludovico; Donzelli, Stefano; Tordini, Alessandra; Parise, Antonio; Pirozzi, Ciro; Di Meo, Federica; Marallo, Carmine; Pace, Vincenzo; Marini, Chiara; Carreras, Giovanni.
  • Lazzari L; SSD of Clinical and Interventional Arrhythmology, 'S. Maria', Terni.
  • Donzelli S; SSD of Clinical and Interventional Arrhythmology, 'S. Maria', Terni.
  • Tordini A; SSD of Clinical and Interventional Arrhythmology, 'S. Maria', Terni.
  • Parise A; SSD of Clinical and Interventional Arrhythmology, 'S. Maria', Terni.
  • Pirozzi C; Cardiology, University of Perugia.
  • Di Meo F; Cardiology Unit, 'S. Maria della Pietà', Nola.
  • Marallo C; SSD of Clinical and Interventional Arrhythmology, 'S. Maria', Terni.
  • Pace V; SC of Cardiology, 'S. Maria', Terni.
  • Marini C; Department of Medical Biotechnology, University of Siena.
  • Carreras G; SSD of Clinical and Interventional Arrhythmology, 'S. Maria', Terni.
Eur Heart J Suppl ; 26(Suppl 1): i44-i48, 2024 Apr.
Article en En | MEDLINE | ID: mdl-38867867
ABSTRACT
Arrhythmic storm is a clinical emergency associated with high mortality, which requires multi-disciplinary management. Reprogramming of the implantable cardiac defibrillator (ICD) aimed at reducing shocks, adrenergic blockade using beta-blockers, sedation/anxiolysis, and blockade of the stellate ganglion represent the first simple and effective manoeuvres, but further suppression of arrhythmias with antiarrhythmics is often required. A low-risk patient (e.g. monomorphic ventricular tachycardia, functioning ICD, and haemodynamically stable) should be managed with a beta-blocker (possibly non-selective) plus amiodarone, in addition to sedation with a benzodiazepine or dexmedetomidine; in patients at greater risk (high burden and haemodynamic instability), autonomic modulation with blockade of the stellate ganglion and the addition of a second antiarrhythmic (lidocaine) should be considered. In patients refractory to these measures, with advanced heart failure, general anaesthesia with intubation and the establishment of a haemodynamic circulatory support should be considered. Ablation, performed early, appears to be superior in terms of mortality and reduction of future shocks compared with titration of antiarrhythmics.
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