Quantitative management of human faecal bulking response to combinations of functionally distinct dietary fibers, using functional equivalents and a validated rat model.
Int J Food Sci Nutr
; 75(5): 518-526, 2024 Aug.
Article
en En
| MEDLINE
| ID: mdl-38910266
ABSTRACT
Functionally distinct dietary fibre sources may be combined in reformulated foods to restore a natural spectrum of health attributes. Effects of wheat bran (WB), psyllium husk, guar gum and Raftilose™ combinations on hydrated faecal mass (HFM), were determined. A valid rat model was fed diets supplemented with 10% WB, 10% WB with 1-6% psyllium in 1% steps, and 10% WB/5% psyllium with 1-7% guar gum or 1-6% Raftilose in 1% steps. Fully hydrated faecal pellets gave HFM values in the human range, increasing by 2.4 ± 0.29 g per gram of WB ingested, and by 15.6 ± 1.52 g per g of psyllium. Equations for incremental changes in HFM predicted intakes of fibre combinations required for adequate daily HFM, and it is shown how expressing relative effects of foods on HFM as functional equivalents would allow quantitative personalised management of HFM for reduced constipation and colorectal cancer in humans.
Palabras clave
Texto completo:
1
Banco de datos:
MEDLINE
Asunto principal:
Psyllium
/
Fibras de la Dieta
/
Gomas de Plantas
/
Heces
/
Galactanos
/
Mananos
Límite:
Animals
/
Humans
/
Male
Idioma:
En
Año:
2024
Tipo del documento:
Article