Analysis of optical properties and response mechanism of H2S fluorescent probe based on rhodamine derivatives.
Spectrochim Acta A Mol Biomol Spectrosc
; 321: 124745, 2024 Nov 15.
Article
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| MEDLINE
| ID: mdl-38955071
ABSTRACT
H2S plays a crucial role in numerous physiological and pathological processes. In this project, a new fluorescent probe, SG-H2S, for the detection of H2S, was developed by introducing the recognition group 2,4-dinitrophenyl ether. The combination of rhodamine derivatives can produce both colorimetric reactions and fluorescence reactions. Compared with the current H2S probes, the main advantages of SG-H2S are its wide pH range (5-9), fast response (30 min), and high selectivity in competitive species (including biological mercaptan). The probe SG-H2S has low cytotoxicity and has been successfully applied to imaging in MCF-7 cells, HeLa cells, and BALB/c nude mice. We hope that SG-H2S will provide a vital method for the field of biology.
Palabras clave
Texto completo:
1
Banco de datos:
MEDLINE
Asunto principal:
Rodaminas
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Espectrometría de Fluorescencia
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Colorantes Fluorescentes
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Sulfuro de Hidrógeno
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Ratones Endogámicos BALB C
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Ratones Desnudos
Límite:
Animals
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Humans
Idioma:
En
Año:
2024
Tipo del documento:
Article