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Overview of acute seizure management in US nursing homes.
O'Dwyer, Rebecca; Leppik, Ilo E; Eads, Pam; Long, Yuhan; Birnbaum, Angela K.
  • O'Dwyer R; Department of Neurological Science, Rush University Medical Center, Chicago, IL, USA. Electronic address: rebecca_odwyer@rush.edu.
  • Leppik IE; Experimental and Clinical Pharmacology, College of Pharmacy, University of Minnesota, Minneapolis, MN, USA; Department of Neurology, University of Minnesota, Minneapolis, MN, USA.
  • Eads P; UCB Pharmaceuticals, Smyrna, GA, USA.
  • Long Y; Experimental and Clinical Pharmacology, College of Pharmacy, University of Minnesota, Minneapolis, MN, USA.
  • Birnbaum AK; Experimental and Clinical Pharmacology, College of Pharmacy, University of Minnesota, Minneapolis, MN, USA.
Epilepsy Behav ; 158: 109913, 2024 Sep.
Article en En | MEDLINE | ID: mdl-38959744
ABSTRACT

INTRODUCTION:

Residents in NH are more likely to be diagnosed with epilepsy or seizures, which are associated with higher mortality and complicate care. This setting provides unique challenges in the treatment of seizures however, little is known about current management practices in NH. Most studies in the literature concentrate on the use of antiseizure medications (ASMs) but little is known about the management of the acute seizure and clinical guidance is needed to ensure the safety of this vulnerable population. The objective of this study was to survey current practices, identifying knowledge deficits and inform future educational endeavors, including acute seizure action plans (ASAPs).

METHODS:

A survey was developed pertaining to a broad spectrum of clinical aspects in the management of acute seizures in NH, distinguishing first time seizures from those in the setting of a known seizure disorder. It was sent to NH medical directors throughout the US and data was gathered from those who had at least one new case of new onset/epilepsy in the last 3 years.

RESULTS:

Ninety-one NH directors responded with 52 % having a seizure protocol. Nurses are responsible in the majority of cases for protocol activation. Regardless of the patient's seizure history, rescue medications are given in the majority of cases, oral benzodiazepines, followed by intravenous and then rectal benzodiazepines. Newer intranasal and intramuscular formulations of benzodiazepines were less frequently prescribed. The most commonly prescribed ASM is levetiracetam, followed by lamotrigine, valproic acid and phenytoin. Staff training and in-service education occur infrequently. Respondents thought no-cost seizure education would be highly beneficial. CONCLUSIONS AND IMPLICATIONS Only approximately half of NH have protocols for the acute management of seizures. Rescue medications are given regardless of seizure history and often older ASMs are used for long-term management. Our study highlights areas of knowledge deficits and treatment areas for improvement, identifying the need and potential for ASAPs in NHs.
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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Convulsiones / Anticonvulsivantes / Casas de Salud Límite: Female / Humans / Male País como asunto: America do norte Idioma: En Año: 2024 Tipo del documento: Article

Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Convulsiones / Anticonvulsivantes / Casas de Salud Límite: Female / Humans / Male País como asunto: America do norte Idioma: En Año: 2024 Tipo del documento: Article