Interpretation of Data from Translational Rodent Nerve Injury and Repair Models.
Hand Clin
; 40(3): 429-440, 2024 08.
Article
en En
| MEDLINE
| ID: mdl-38972687
ABSTRACT
This article highlights the use of rodents as preclinical models to evaluate the management of nerve injuries, describing the pitfalls and value from rodent nerve injury and regeneration outcomes, as well as treatments derived from these rodent models. The anatomic structure, size, and cellular and molecular differences and similarities between rodent and human nerves are summarized. Specific examples of success and failure when assessing outcome metrics are presented for context. Evidence for translation to clinical practice includes the topics of electrical stimulation, Tacrolimus (FK506), and acellular nerve allografts.
Palabras clave
Texto completo:
1
Banco de datos:
MEDLINE
Asunto principal:
Modelos Animales de Enfermedad
/
Traumatismos de los Nervios Periféricos
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Regeneración Nerviosa
Límite:
Animals
/
Humans
Idioma:
En
Año:
2024
Tipo del documento:
Article