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Poorly Cohesive Carcinoma of the Nonampullary Small Bowel: A Rare Cause of Recurrent Small Bowel Obstruction.
Lee, Brian J; Guzman, Jesus; Padilla, Osvaldo; Laks, Shaked; Ng, Nathaniel; Elhanafi, Sherif E; Badillo, Ricardo; Zuckerman, Marc J.
  • Lee BJ; Department of Internal Medicine, Texas Tech University Health Sciences Center El Paso, El Paso, TX.
  • Guzman J; Division of Gastroenterology, Texas Tech University Health Sciences Center El Paso, El Paso, TX.
  • Padilla O; Department of Pathology, Texas Tech University Health Sciences Center El Paso, El Paso, TX.
  • Laks S; Department of Radiology, Texas Tech University Health Sciences Center El Paso, El Paso, TX.
  • Ng N; Department of Surgery, Texas Tech University Health Sciences Center El Paso, El Paso, TX.
  • Elhanafi SE; Division of Gastroenterology, Texas Tech University Health Sciences Center El Paso, El Paso, TX.
  • Badillo R; Division of Gastroenterology, Texas Tech University Health Sciences Center El Paso, El Paso, TX.
  • Zuckerman MJ; Division of Gastroenterology, Texas Tech University Health Sciences Center El Paso, El Paso, TX.
ACG Case Rep J ; 11(7): e01439, 2024 Jul.
Article en En | MEDLINE | ID: mdl-39021717
ABSTRACT
Poorly cohesive carcinoma (PCC) is an uncommon neoplasm characterized by tumorous cells exhibiting a lack of adhesion. PCC has been reported rarely in the small intestine other than at the ampulla of Vater. We present a 40-year-old man with recurrent abdominal pain and small bowel obstruction. Imaging revealed an abnormal appearing distal small bowel, with only nonspecific mucosal changes discovered on antegrade and retrograde enteroscopy. On subsequent diagnostic laparoscopy, an ileal mass was found and resected with histopathology showing PCC with signet ring formation. This is an aggressive cancer with a worse prognosis than other small bowel adenocarcinomas.
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