Impact of cumulative dose of hydroxychloroquine on retinal structures.
Graefes Arch Clin Exp Ophthalmol
; 2024 Aug 19.
Article
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| MEDLINE
| ID: mdl-39160441
ABSTRACT
KEY MESSAGES What is known ⢠Hydroxychloroquine (HCQ) is widely used for autoimmune disorders but is associated with the risk of retinal toxicity. ⢠Early detection of retinal structural changes due to HCQ toxicity remains challenging, and cumulative HCQ dose as a risk factor has conflicting clinical relevance. What Is New ⢠Higher cumulative HCQ doses are significantly associated with thinner outer retinal layers (foveal, parafoveal, and perifoveal regions). ⢠No significant associations were found between HCQ cumulative dose and inner retinal thickness or age.
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2024
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