Micro-transplantation in an elderly patient with very high risk MDS:A case report and literature review.

Wu, Kangli; Liu, Mingsuo; Wu, Yajun; Luo, Qiulian; Chen, Jin; Xu, Wanling; Yang, Xixi; Hong, Piaoru; Qu, Zhigang.

Wu K; Department of hematology, Yiwu Central Hospital, Yiwu, Zhejiang Province, 322099, China.
Liu M; Department of hematology, Yiwu Central Hospital, Yiwu, Zhejiang Province, 322099, China.
Wu Y; Department of hematology, Yiwu Central Hospital, Yiwu, Zhejiang Province, 322099, China.
Luo Q; Department of hematology, Yiwu Central Hospital, Yiwu, Zhejiang Province, 322099, China.
Chen J; Department of hematology, Yiwu Central Hospital, Yiwu, Zhejiang Province, 322099, China.
Xu W; Department of hematology, Yiwu Central Hospital, Yiwu, Zhejiang Province, 322099, China.
Yang X; Department of hematology, Yiwu Central Hospital, Yiwu, Zhejiang Province, 322099, China.
Hong P; Department of hematology, Yiwu Central Hospital, Yiwu, Zhejiang Province, 322099, China.
Qu Z; Department of hematology, Yiwu Central Hospital, Yiwu, Zhejiang Province, 322099, China.

Leuk Res Rep ; 22: 100475, 2024.

Article en En | MEDLINE | ID: mdl-39171150

ABSTRACT

Introduction:

The prognosis of patients with myelodysplastic syndromes (MDS) (very high risk) is poor.HLA-mismatched allogeneic T-cell infusion which is called micro-transplantation can not only shorten the time of bone marrow suppression, but also improve the treatment response of patients. Case presentation A 74-year-old woman presented with fatigue and showed pancytopenia on routine blood count. She was diagnosed with MDS (very high risk) after bone marrow examination,then she received 4 cycles of micro-transplantation. The progression-free survival was 22 months and overall survival was 33 months.