Sheep and goats as reservoirs of colistin-resistant E. coli: first detection of ETEC ST10 and E. coli ST6396 mcr-1 positive strains in North Africa.
J Appl Microbiol
; 135(9)2024 Sep 02.
Article
en En
| MEDLINE
| ID: mdl-39223099
ABSTRACT
AIM:
This study aimed to screen and characterize colistin-resistant strains isolated from different livestock species in Algeria, including sheep, goats, and dromedaries. METHODS ANDRESULTS:
A total of 197 rectal and nasal swabs were screened for colistin-resistant Gram-negative bacilli. Twenty one isolates were selected, identified, and their antibiotic resistance was phenotypically and genotypically characterized. The majority (15/21) were affiliated to Escherichia coli, from which 4 strains isolated from sheep (n = 2) and goats (n = 2) and belonging to phylogroup A and ST10 and ST6396 lineages, respectively, carried the mcr-1 gene. The remaining isolates were identified as belonging to the following genera Raoultella, Enterobacter, Klebsiella, and Pseudomonas.CONCLUSION:
This study highlights the presence of virulent and multiresistant Gram-negative bacilli in farm animals, increasing the risk of transmitting potentially fatal infections to humans.Palabras clave
Texto completo:
1
Banco de datos:
MEDLINE
Asunto principal:
Cabras
/
Colistina
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Proteínas de Escherichia coli
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Infecciones por Escherichia coli
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Antibacterianos
Límite:
Animals
País como asunto:
Africa
Idioma:
En
Año:
2024
Tipo del documento:
Article