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Advancements and challenges in stem cell transplantation for regenerative medicine.
Wei, Lingxi; Yan, Wenqi; Shah, Wahid; Zhang, Zhengwei; Wang, Minghe; Liu, Biao; Xue, Zhentong; Cao, Yixin; Hou, Xinyu; Zhang, Kai; Yan, Beibei; Wang, Xiaogang.
  • Wei L; Shanxi Medical University, Tai Yuan, Shanxi, 030607, China.
  • Yan W; Shandong University, Ji Nan, Shandong, 250000, China.
  • Shah W; Shanxi Medical University, Tai Yuan, Shanxi, 030607, China.
  • Zhang Z; Department of Ophthalmology, Jiangnan University Medical Center, Wuxi, Jiangsu, 214002, China.
  • Wang M; Shanxi Medical University, Tai Yuan, Shanxi, 030607, China.
  • Liu B; Shanxi Medical University, Tai Yuan, Shanxi, 030607, China.
  • Xue Z; Shanxi Medical University, Tai Yuan, Shanxi, 030607, China.
  • Cao Y; Shanxi Medical University, Tai Yuan, Shanxi, 030607, China.
  • Hou X; School of Geographic Sciences, Hebei Normal University, Shijiazhuang, 050024, China.
  • Zhang K; Shanxi Medical University, Tai Yuan, Shanxi, 030607, China.
  • Yan B; Shanxi Medical University, Tai Yuan, Shanxi, 030607, China.
  • Wang X; Department of Cataract, Shanxi Eye Hospital Affiliated to Shanxi Medical University, Taiyuan, 030002, China.
Heliyon ; 10(16): e35836, 2024 Aug 30.
Article en En | MEDLINE | ID: mdl-39247380
ABSTRACT
Stem cell transplantation has emerged as a promising avenue in regenerative medicine, potentially facilitating tissue repair in degenerative diseases and injuries. This review comprehensively examines recent developments and challenges in stem cell transplantation. It explores the identification and isolation of various stem cell types, including embryonic, induced pluripotent, and adult stem cells derived from multiple sources. Additionally, the review highlights the tissue-specific applications of these stem cells, focusing on bone and cartilage regeneration, treatment of neurological disorders, and management of hematological conditions. Future advancements and effective resolution of current challenges will be crucial in fully realizing the potential of stem cell transplantation in regenerative medicine. With responsible and ethical practices, the field can potentially transform disease and injury treatment, ultimately improving the quality of life for countless individuals.
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