Danazol in the management of ureteral obstruction secondary to endometriosis.
Fertil Steril
; 44(2): 274-6, 1985 Aug.
Article
en En
| MEDLINE
| ID: mdl-4018283
ABSTRACT
Ureteral obstruction caused by endometriosis is uncommon. It is, however, an important complication that imposes a 25% chance for permanent loss of renal function on the affected side. The standard management is surgical; however, three cases have been reported in which regression of obstruction followed medical therapy. This case report concerns a patient with long-standing partial ureteric obstruction due to endometriosis who was treated for 2 months with danazol. Clinical response of the endometriosis was excellent, but the obstruction persisted, a retroperitoneal ureteroneocystotomy was therefore performed. The ureter was found to be obstructed by dense fibrous tissue that contained endometrial glands. It seems therefore that a trial of danazol may be attempted in selected cases, but that the drug is unlikely to relieve endometriotic ureteric obstruction once dense fibrosis has occurred.
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Banco de datos:
MEDLINE
Asunto principal:
Pregnadienos
/
Neoplasias Ureterales
/
Obstrucción Ureteral
/
Danazol
/
Endometriosis
Límite:
Adult
/
Female
/
Humans
Idioma:
En
Año:
1985
Tipo del documento:
Article