Leukocyte alkaline phosphatase relative score and basal body temperature as indicators of ovulation during menstrual cycles terminated by normal full-term pregnancies.

PIP: Leukocyte alkaline phosphatase relative score (LAP-RS) and basal body temperature (BBT) as indicators of ovulation during menstrual cycles terminated by normal full-term pregnancies were assessed in 5 cycles terminated by full-term pregnancies. For 3 of the cycles the LAP-RS appeared on the day of luteinizing hormone (LH) surge and 24 hours after the day of maximal total estrogen excretion. For the remaining 2 cycles the LAP-RS peak occurred the day before the LH surge. A wide range of absolute basal and peak LAP values was observed but the ratio between the basal and peak determination was similar (5.8). This suggested that ovulation may be predicted by a sudden increase of LAP-RS to mean values 5 times higher than the basal preovulatory level. BBTs indicated ovulation more than 24 hours after the LH surge in 2 of 5 cycles, indicating that this test is unsatisfactory for the purpose of predicting and pinpointing ovulation. These data were supported by a 2nd group of 6 women who were monitored by LAP-RS throughout their menstrual cycles, and conceived after insemination and administration of human chorionic gonadotropin.^ieng