Reduction of coronary blood flow during coronary artery spasm occurring spontaneously and after provocation by ergonovine maleate.
Circulation
; 57(2): 392-5, 1978 Feb.
Article
en En
| MEDLINE
| ID: mdl-618632
ABSTRACT
A 50-year-old man suffering from recurrent chest pain accompanied by transient ST-segment elevation developed spasm of the left anterior descending coronary artery after receiving ergonovine maleate. During spontaneous chest pain, thermodilution coronary sinus blood flow fell from 96 ml/min to 46 ml/min, while the coronary sinsu arteriovenous oxygen difference widened from 9.82 volumes percent to 11.3 volumes percent. During spontaneous relief of pain, coincident with resolution of the ST-segment changes, coronary sinus blood flow gradually rose to 135 ml/min, while coronary sinus arteriovenous oxygen difference narrowed to 6.82 volumes percent. Similar aterations in coronoary sinus blood flow accompanied chest pain provoked by ergonovine maleate. A thallium-201 scan confirmed a perfusion defect in the distribution the left anterior descending coronary artery. Thus, coronary artery spasm can produce a marked deficity in coronary blood flow that is associated with increased myocardial oxygen extraction; release of spasm creates a hyperemic response.
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Banco de datos:
MEDLINE
Asunto principal:
Espasmo
/
Circulación Coronaria
/
Vasos Coronarios
/
Ergonovina
Límite:
Humans
/
Male
/
Middle aged
Idioma:
En
Año:
1978
Tipo del documento:
Article