Carbohydrate metabolites in the blood and CSF of patients with neuromuscular disorders.
J Neurol
; 226(2): 111-8, 1981.
Article
en En
| MEDLINE
| ID: mdl-6186780
ABSTRACT
The concentrations of glucose, pyruvate and lactate were determined in the blood and lumbar CSF of 63 patients with neuromuscular disorders and 40 controls. The glucose/lactate and lactate/pyruvate ratios were also calculated, in addition to the cytoplasmic NADH/NAD+ (nicotinamide-adenine dinucleotide-H/nicotinamide-adenine dinucleotide) ratio in the brain. Remarkable deviations from control values were found not only in blood but also in the CSF of patients with different neuromuscular diseases, particularly in Duchenne muscular dystrophy and peroneal muscular atrophy, indicative of disturbance of the carbohydrate metabolism in the central nervous system.
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Banco de datos:
MEDLINE
Asunto principal:
Enfermedades Neuromusculares
Límite:
Humans
Idioma:
En
Año:
1981
Tipo del documento:
Article