Monoamine metabolism during chronic benzodiazepine treatment and withdrawal.
Biol Psychiatry
; 18(2): 207-13, 1983 Feb.
Article
en En
| MEDLINE
| ID: mdl-6187380
ABSTRACT
Long-term normal-dose benzodiazepine treatment in seven patients was associated with reduced urinary excretion of MOPEG (4-hydroxy-3-methoxy-phenylglycol). Following the discontinuation of the drugs a characteristic withdrawal reaction occurred, with an increase towards normal values of the MOPEG excretion levels and changes in the excretion of 5-HIAA (5-hydroxyindoleacetic acid). No significant changes in the 24-hr urinary excretion of free cortisol or HMMA (3-methoxy-hydroxy-mandelic acid) were detected.
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Banco de datos:
MEDLINE
Asunto principal:
Fenilacetatos
/
Síndrome de Abstinencia a Sustancias
/
Ansiolíticos
/
Glicoles
/
Ácido Homovanílico
/
Ácido Hidroxiindolacético
/
Metoxihidroxifenilglicol
Tipo de estudio:
Clinical_trials
Límite:
Adult
/
Female
/
Humans
/
Male
Idioma:
En
Año:
1983
Tipo del documento:
Article