[Relation between asymmetrical hypertrophy of the interventricular septum and plasma levels of catecholamines in normotensive chronic uremic patients undergoing hemodialysis treatment]. / Relazione tra ipertrofia asimmetrica del setto interventricolare e concentrazione plasmatica di catecolamine in pazienti uremici cronici normotesi in trattamento emodialitico.
G Ital Cardiol
; 14(12): 999-1005, 1984 Dec.
Article
en It
| MEDLINE
| ID: mdl-6241912
ABSTRACT
Sympathetic-adrenergic activity has been evaluated in 23 chronic uremic, normotensive patients on regular hemodialysis, 7 of which (30.4%) with M-mode and bidimensional echocardiographic finding of asymmetric septal hypertrophy. The sympathetic function has been assessed by measuring arterial plasma norepinephrine and epinephrine levels before and after postural activation, just before and after dialysis. After dialysis, standing caused a significant increase of plasma norepinephrine levels in patients with asymmetric septal hypertrophy in comparison with patients without asymmetric septal hypertrophy and with the control non uremic group. Moreover, a significant decrease in blood pressure and a sharp heart rate increase were noted in the patients without asymmetric septal hypertrophy, whereas mean blood pressure and heart rate were unchanged in the patients with asymmetric septal hypertrophy. These results suggest that increased plasma norepinephrine concentration may have a role in the development of interventricular septal hypertrophy.
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Banco de datos:
MEDLINE
Asunto principal:
Uremia
/
Epinefrina
/
Norepinefrina
/
Cardiomegalia
/
Tabiques Cardíacos
Límite:
Adult
/
Aged
/
Female
/
Humans
/
Male
/
Middle aged
Idioma:
It
Año:
1984
Tipo del documento:
Article