Variable-region sequences of five human lambda-chain proteins reacting with an idiotypic antibody to the MCG Bence-Jones protein.
Mol Immunol
; 20(10): 1107-16, 1983 Oct.
Article
en En
| MEDLINE
| ID: mdl-6425645
ABSTRACT
An antibody to the V-region of BJ protein MCG has been used to detect other human lambda-chains with similar idiotypic specificities. Five such proteins have been found and sequenced. They show relatively strong sequence homologies to some segments of the MCG V-region. The results of this study indicate that L-chains which contain short segments of their V-regions that are identical can be readily detected by the use of appropriate antisera.
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Banco de datos:
MEDLINE
Asunto principal:
Proteína de Bence Jones
/
Región Variable de Inmunoglobulina
/
Cadenas lambda de Inmunoglobulina
/
Cadenas Ligeras de Inmunoglobulina
/
Idiotipos de Inmunoglobulinas
Límite:
Humans
Idioma:
En
Año:
1983
Tipo del documento:
Article