Characterization of the exposed carbohydrates on the sheath surface of in vitro-derived Brugia pahangi microfilariae by analysis of lectin binding.
J Parasitol
; 69(6): 1043-7, 1983 Dec.
Article
en En
| MEDLINE
| ID: mdl-6674454
ABSTRACT
Adult female Brugia pahangi were maintained metabolically active in vitro for up to 35 days in Click's medium supplemented with 10% horse serum. For the first 14 to 18 days microfilariae were released into culture. Although these in vitro-derived microfilariae were morphologically identical to in vivo-derived microfilariae, they could be differentiated by their characteristic of binding to a panel of fluorescein-conjugated lectins. The results suggest that maturation and release of microfilariae are correlated with glycosidic alterations on the sheath surface.
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Banco de datos:
MEDLINE
Asunto principal:
Brugia
/
Carbohidratos
/
Filarioidea
/
Microfilarias
Límite:
Animals
Idioma:
En
Año:
1983
Tipo del documento:
Article