Experimental infection with Basidiobolus haptosporus.

ABSTRACT

The authors tried to reproduce experimentally the Basidiobolus haptosporus infection. Culture forms of the fungus were inoculated in 26 adult hamsters, in two newborn hamsters and in two marmosets. Oral, intratesticular, intrahepatic, intraperitonial and subcutaneous inoculations were made. Bethametasone was given prior to inoculation in a group of animals. The lesions produced were only of the foreign body type and there was no development of the fungus in the animal tissues. The AA concluded that an experimental model for the B. haptosporus infection has not yet been found.