Application of the Salmonella typhimurium microsome test to the study of 25 drugs belonging to 5 chemical series.
Mutat Res
; 77(4): 301-6, 1980 Apr.
Article
en En
| MEDLINE
| ID: mdl-6990247
ABSTRACT
25 active-principle forms of pharmaceutical drugs belonging to 5 chemical series have been tested for mutagenic activity. To screen these drugs we used the Salmonella typhimurium assay on 5-histidine-requiring strains, with and without microsomal activation. Only the 3 nitroimidazole derivatives were mutagenic for strains TA100, TA1535 and TA98.
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Banco de datos:
MEDLINE
Asunto principal:
Reserpina
/
Estrógenos
/
Guanidinas
/
Antiinflamatorios
/
Mutágenos
/
Nitroimidazoles
Idioma:
En
Año:
1980
Tipo del documento:
Article