Effect of a new non-steroidal anti-inflammatory drug, nitroflurbiprofen, on the expression of inducible nitric oxide synthase in rat neutrophils.
Br J Pharmacol
; 115(2): 225-6, 1995 May.
Article
en En
| MEDLINE
| ID: mdl-7545516
ABSTRACT
The effects of a non-steroidal anti-inflammatory drug, flurbiprofen, and its nitro-derivative, nitroflurbiprofen, on inducible nitric oxide synthase in rat neutrophils were examined. Nitroflurbiprofen was shown to inhibit nitric oxide synthase induction caused by lipopolysaccharide administration, while flurbiprofen had no effect on nitric oxide synthase induction. This inhibitory action may be ascribed to nitric oxide released from nitroflurbiprofen.
Texto completo:
1
Banco de datos:
MEDLINE
Asunto principal:
Antiinflamatorios no Esteroideos
/
Flurbiprofeno
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Aminoácido Oxidorreductasas
/
Neutrófilos
Límite:
Animals
Idioma:
En
Año:
1995
Tipo del documento:
Article