Hepatitis C virus antibody in multiply transfused Chinese with thalassaemia major.
Bone Marrow Transplant
; 12 Suppl 1: 26-8, 1993.
Article
en En
| MEDLINE
| ID: mdl-7690634
ABSTRACT
Thirty-four of 99 multiply transfused Chinese (49 females, 50 males) with thalassaemia major were positive for antibody to hepatitis C virus. There was no sex predominance in seropositivity with 18 females and 16 males positive. The mean (+/- SD) age and units of blood transfused were significantly higher in the seropositive patients (167 +/- 48 months, 206 +/- 82 units respectively) than the seronegative patients (113 +/- 56 months, 124 +/- 80 units respectively). The seropositive patients had higher mean (+/- SD) serum alanine aminotransferase, aspartate aminotransferase and ferritin concentrations (91 +/- 82 IU/L, 67 +/- 38 IU/L, 4797 +/- 2522 ng/ml respectively) than the seronegative patients (38 +/- 29 IU/L, 48 +/- 28 IU/L, 3620 +/- 2140 ng/ml respectively). Serum ferritin had an independent and significant effect on serum alanine aminotransferase in addition to that of seropositivity to hepatitis C virus.
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Banco de datos:
MEDLINE
Asunto principal:
Anticuerpos Antihepatitis
/
Hepatitis C
/
Talasemia beta
/
Hepacivirus
Tipo de estudio:
Prevalence_studies
/
Risk_factors_studies
Límite:
Child
/
Child, preschool
/
Female
/
Humans
/
Infant
/
Male
País como asunto:
Asia
Idioma:
En
Año:
1993
Tipo del documento:
Article