Sodium-dependent receptor current in a new mechanoreceptor preparation.
J Neurophysiol
; 72(6): 3026-8, 1994 Dec.
Article
en En
| MEDLINE
| ID: mdl-7897509
ABSTRACT
1. Intracellular microelectrodes recorded the receptor potential and receptor current in the neurons of spider slit sense organs during mechanical stimulation of the slits. 2. Mechanical stimulation produced two patterns of action potential discharge, corresponding to the two groups of neurons described previously by electrical stimulation. 3. Tetrodotoxin eliminated the action potentials and revealed a receptor potential with both static and adapting components. Voltage clamp gave an inward receptor current with a similar time course. 4. Replacement of sodium ions in the bath reversibly eliminated the receptor current, indicating that it is carried by sodium ions. However, this effect was comparatively slow, suggesting that the tips of the sensory dendrites lie in a chemically restricted environment.
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Banco de datos:
MEDLINE
Asunto principal:
Sodio
/
Arañas
/
Canales de Sodio
/
Mecanorreceptores
/
Neuronas
Límite:
Animals
Idioma:
En
Año:
1994
Tipo del documento:
Article