The pharmacokinetic-pharmacodynamic (Digit Symbol Substitution Test) relationship of flumazenil in a midazolam steady-state model in healthy volunteers.

Zhi, J; Massarella, J W; Melia, A T; Teller, S B; Schmitt-Muskus, J; Crews, T; Oldfield, N; Erb, R J; Leese, P T; Patel, I H

Zhi, J; Massarella, J W; Melia, A T; Teller, S B; Schmitt-Muskus, J; Crews, T; Oldfield, N; Erb, R J; Leese, P T; Patel, I H.

Zhi J; Department of Clinical Pharmacokinetics, Hoffman-La Roche, Inc., Nutley, NJ 07110-1199.

Clin Pharmacol Ther ; 56(5): 530-6, 1994 Nov.

Article en En | MEDLINE | ID: mdl-7955817

Asunto(s)

Flumazenil/farmacología; Flumazenil/farmacocinética; Midazolam/antagonistas & inhibidores; Desempeño Psicomotor/efectos de los fármacos; Adulto; Estudios Cruzados; Método Doble Ciego; Flumazenil/sangre; Humanos; Masculino; Midazolam/sangre

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Banco de datos: MEDLINE Asunto principal: Desempeño Psicomotor / Midazolam / Flumazenil Tipo de estudio: Clinical_trials / Prognostic_studies Límite: Adult / Humans / Male Idioma: En Año: 1994 Tipo del documento: Article

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