[Preparation and structural elucidation of insularine-N-oxides].
Yao Xue Xue Bao
; 28(7): 557-60, 1993.
Article
en Zh
| MEDLINE
| ID: mdl-8285061
ABSTRACT
Oxidation of insularine (I) with m-chloroperbenzoic acid yielded four insularine-N-oxides. Two of them are identical in every respect with our insularine-2 beta-N-oxide (II) and insularine-2' beta-N-oxide (III), two rare examples of naturally occurring head-to-tail bisbenzylisoquinoline N-oxides newly isolated from Cyclea sutchuenensis, which confirmed the structures of the two novel natural N-oxides. The other two are new compounds and their structures have been established as insularine-2' alpha-N-oxide (IV) and insularine-2 beta,2' beta-N, N-dioxide (V), on the basis of spectral data (UV, IR, 1HNMR, NOEDS AND MS) analysis.
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Banco de datos:
MEDLINE
Asunto principal:
Medicamentos Herbarios Chinos
/
Óxidos N-Cíclicos
/
Isoquinolinas
Idioma:
Zh
Año:
1993
Tipo del documento:
Article