Detection of an oestrogen receptor-like protein in human meningiomas by band shift assay using a synthetic oestrogen responsive element (ERE).
Br J Cancer
; 68(2): 290-4, 1993 Aug.
Article
en En
| MEDLINE
| ID: mdl-8347484
ABSTRACT
When a ligand binding or enzyme immunoassay is used, meningiomas are found to be rich in progestin receptors (PR) whereas oestrogen receptors (ER) are virtually undetectable. A protein that can bind to an oestrogen responsive element (ERE) was detected in meningiomas, by using the band-shift assay. The binding of ER to the ERE is inhibited by the anti-ER monoclonal antibody ER-P31, which is directed to the A/B domain of the ER, indicating that the binding protein is an ER-like protein.
Texto completo:
1
Banco de datos:
MEDLINE
Asunto principal:
Receptores de Estrógenos
/
Neoplasias Meníngeas
/
Meningioma
Tipo de estudio:
Diagnostic_studies
Límite:
Female
/
Humans
Idioma:
En
Año:
1993
Tipo del documento:
Article