Transient transfection and expression in the obligate intracellular parasite Toxoplasma gondii.
Science
; 260(5106): 349-52, 1993 Apr 16.
Article
en En
| MEDLINE
| ID: mdl-8469986
ABSTRACT
Toxoplasma gondii is a protozoan pathogen that produces severe disease in humans and animals. This obligate intracellular parasite provides an excellent model for the study of how such pathogens are able to invade, survive, and replicate intracellularly. DNA encoding chloramphenicol acetyltransferase was introduced into T. gondii and transiently expressed with the use of three vectors based on different Toxoplasma genes. The ability to introduce genes and have them efficiently and faithfully expressed is an essential tool for understanding the structure-function relation of genes and their products.
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Banco de datos:
MEDLINE
Asunto principal:
Toxoplasma
/
Transfección
/
Expresión Génica
/
Genes Protozoarios
Límite:
Animals
/
Humans
Idioma:
En
Año:
1993
Tipo del documento:
Article