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Conjunctival intraepithelial neoplasia. A possible marker for human immunodeficiency virus infection?
Karp, C L; Scott, I U; Chang, T S; Pflugfelder, S C.
  • Karp CL; Bascom Palmer Eye Institute, University of Miami School of Medicine, Florida 33136, USA.
Arch Ophthalmol ; 114(3): 257-61, 1996 Mar.
Article en En | MEDLINE | ID: mdl-8600883
ABSTRACT

BACKGROUND:

Conjunctival intraepithelial neoplasia has traditionally been found at the limbus in elderly individuals. Recently, this ocular tumor has been observed in younger patients.

OBJECTIVE:

To investigate the potential association of human immunodeficiency virus infection with the emergence of this atypical presentation of conjunctival intraepithelial neoplasia. DESIGN, SETTING, AND

PARTICIPANTS:

Records of patients at the Bascom Palmer Eye Institute (Miami, Fla) in whom conjunctival intraepithelial neoplasia was diagnosed between January 1, 1991, and December 31, 1993, were reviewed. Attempts were made to contact those patients younger than 50 years for clinical evaluation and human immunodeficiency virus serologic testing.

RESULTS:

Conjunctival intraepithelial neoplasia was diagnosed in 73 patients during the study period. Of the nine patients younger than 50 years, six were available for serologic testing. Three (50%) of these individuals were found to be positive for human immunodeficiency virus.

CONCLUSION:

Human immunodeficiency virus testing and counseling should be considered in patients younger than 50 years in whom conjunctival intraepithelial neoplasia is diagnosed.
Asunto(s)
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Banco de datos: MEDLINE Asunto principal: Carcinoma in Situ / Infecciones por VIH / Neoplasias de la Conjuntiva Tipo de estudio: Diagnostic_studies Límite: Adult / Female / Humans / Male / Middle aged Idioma: En Año: 1996 Tipo del documento: Article
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Banco de datos: MEDLINE Asunto principal: Carcinoma in Situ / Infecciones por VIH / Neoplasias de la Conjuntiva Tipo de estudio: Diagnostic_studies Límite: Adult / Female / Humans / Male / Middle aged Idioma: En Año: 1996 Tipo del documento: Article