Is CK-MB isoenzyme useful for diagnosis of cardiac involvement in icteric leptospirosis?
Rev Inst Med Trop Sao Paulo
; 37(5): 461-5, 1995.
Article
en En
| MEDLINE
| ID: mdl-8729758
ABSTRACT
In the absence of heart failure or cardiogenic shock, cardiac involvement diagnosis in icteric leptospirosis is possible on the basis of abnormal electrocardiograms. As metabolic and electrolytic disorders are frequently seen during acute leptospirosis infection, they may be responsible for some electrocardiograms changes. We conducted a study to assess if creatine phosphokinase isoenzyme determinations are useful in selecting patients with a high cardiac involvement suspicion. Sixty-nine patients were studied prospectively. Ten patients out of 16 with cardiac involvement and 25 without had high CK-MB levels (p > 0.05), although mean values of abnormal CK-MB levels were higher in the group with cardiac involvement (p < 0.05). Our analysis indicates that serum CK-MB determination does not provide a specific indicator of myocardial involvement in the course of icteric leptospirosis.
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Banco de datos:
MEDLINE
Asunto principal:
Enfermedad de Weil
/
Creatina Quinasa
/
Cardiopatías
Tipo de estudio:
Diagnostic_studies
/
Observational_studies
/
Risk_factors_studies
Límite:
Adult
/
Female
/
Humans
/
Male
Idioma:
En
Año:
1995
Tipo del documento:
Article