The protein phosphatase 2C (PP2C) superfamily: detection of bacterial homologues.
Protein Sci
; 5(7): 1421-5, 1996 Jul.
Article
en En
| MEDLINE
| ID: mdl-8819174
ABSTRACT
A thorough sequence analysis of the various members of the eukaryotic protein serine/threonine phosphatase 2C (PP2C) family revealed the conservation of 11 motifs. These motifs could be identified in numerous other sequences, including fungal adenylate cyclases that are predicted to contain a functionally active PP2C domain, and a family of prokaryotic serine/threonine phosphatases including SpoIIE. Phylogenetic analysis of all the proteins indicates a widespread sequence family for which a considerable number of isoenzymes can be inferred.
Texto completo:
1
Banco de datos:
MEDLINE
Asunto principal:
Bacterias
/
Fosfoproteínas Fosfatasas
/
Proteínas de Saccharomyces cerevisiae
Tipo de estudio:
Diagnostic_studies
Límite:
Animals
/
Humans
Idioma:
En
Año:
1996
Tipo del documento:
Article