Quasiperiodicity and chaos in cardiac fibrillation.
J Clin Invest
; 99(2): 305-14, 1997 Jan 15.
Article
en En
| MEDLINE
| ID: mdl-9005999
ABSTRACT
In cardiac fibrillation, disorganized waves of electrical activity meander through the heart, and coherent contractile function is lost. We studied fibrillation in three stationary forms in human chronic atrial fibrillation, in a stabilized form of canine ventricular fibrillation, and in fibrillation-like activity in thin sheets of canine and human ventricular tissue in vitro. We also created a computer model of fibrillation. In all four studies, evidence indicated that fibrillation arose through a quasiperiodic stage of period and amplitude modulation, thus exemplifying the "quasiperiodic transition to chaos" first suggested by Ruelle and Takens. This suggests that fibrillation is a form of spatio-temporal chaos, a finding that implies new therapeutic approaches.
Texto completo:
1
Banco de datos:
MEDLINE
Asunto principal:
Periodicidad
/
Arritmias Cardíacas
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Dinámicas no Lineales
Tipo de estudio:
Etiology_studies
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Prognostic_studies
Límite:
Animals
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Humans
Idioma:
En
Año:
1997
Tipo del documento:
Article