Peptides in membranes: tipping the balance of membrane stability.
Trends Biochem Sci
; 22(5): 167-71, 1997 May.
Article
en En
| MEDLINE
| ID: mdl-9175475
ABSTRACT
This review describes a class of peptides that associate with lipids in membranes and are commonly known as 'oblique-orientated peptides'. Owing to an asymmetric distribution of hydrophobic residues along the axis of the alpha-helix, such peptides can destabilize membranes or lipid cores, thereby facilitating such cellular processes as vesicular fusion or protein transport across subcellular compartments, as well as remodelling of lipid cores.
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Banco de datos:
MEDLINE
Asunto principal:
Membrana Celular
/
Proteínas de la Membrana
Tipo de estudio:
Etiology_studies
Idioma:
En
Año:
1997
Tipo del documento:
Article